Human growth hormone has been one of the most potent hormones required for the normal growth of the body. The hormone has been modulated for commercial use to trigger the growth of the muscles. The drug is designed for the initial purpose to treat medical conditions, but it is also used for bodybuilding purposes. The hormone, as well as the associated products, have been largely used by athletes and bodybuilders for their purpose of bulking up and give it a chiseled shape.
In a normal person, the HGH is secreted from the pituitary gland as a response to the signal from the hypothalamus. It depends on the age of the person and related conditions of the body. The natural decrease of HGH occurs as the person ages. However, the hormone level in the body might also decrease due to some diseases. It might occur as a response to some external conditions. It can also result from genetic reasons. To look into the details about the hormone, let us go into the following topics one by one.
Mechanism of HGH production
As stated earlier, HGH is produced by the pituitary gland. The organ is located near the base of the brain and receives direct instructions and signals from the hypothalamus to increase or decrease the secretion of the hormone. The hypothalamus is widely considered as the thermostat of the body. It functions in the maintenance of a series of autonomic functions including body temperature, heart rate, fluid rate, secretions, and also influences sleep, appetite and additional psychological and physiological functions.
Upon reception of the stimulus, the hypothalamus secretes the growth hormone releasing-hormone which binds to its cognate receptor on the pituitary gland. Upon reception of the stimulus, the pituitary gland secretes the HGH hormone.
When the level of the HGH hormone reaches the adequate level, the hypothalamus sends inhibitory signals to the pituitary gland to decrease its production. The inhibitory signal, in this case, is somatostatin.
Effect of Growth hormone on the body
Once released into the blood, the growth hormone initiates the synthesis of IGF-1 (insulin like growth factor-1) and triggers its secretion into the bloodstream. This hormone has been instrumental in the initiation of several processes like cellular growth and replication, repair and rejuvenation of the tissues like muscles. The growth hormone also functions in the growth and elongation of long bones of the body. All these effects culminate in the overall growth of the body.
Why is HGH sale restricted?
There are several associated problems involving HGH. It might result in the damage of the pituitary gland or the hypothalamus resulting from trauma or disease. Some of the side effects on the body include muscle pain, nerve and joint pain, changes in blood sugar level, increased cholesterol levels, edema, and unnatural sensations on the skin as well as muscle weaknesses.
HGH injections have been deemed illegal by all the athletic and sporting organizations in the world. It is always advisable to take the drug when you experience a natural decrease in HGH. Therefore, if you wish to take this drug, consult your physician and get a valid prescription so that you do not get entangled in any sort of legal procedures.